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Biological Safety Cabinets

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Biological Safety Cabinets (BSCs) offer HEPA-filtered airflow and containment for safe handling of biohazards, protecting personnel, samples, and the lab environment.

brand : Bangladesh

Biological Safety Cabinets (BSCs) are critical containment units used in laboratories to safeguard personnel, products, and the environment from exposure to biohazards and airborne contaminants. Designed with high-efficiency particulate air (HEPA) filters and controlled airflow systems, BSCs ensure sterile working conditions while minimizing the risk of cross-contamination and laboratory-acquired infections.

These cabinets are essential in microbiology, virology, pharmaceutical research, and clinical diagnostics, where safe manipulation of infectious agents and sterile techniques are paramount.

✅ Key Features

  • HEPA Filtration: Removes 99.99% of particles ≥0.3 µm for clean air circulation.

  • Laminar Airflow: Ensures uniform air movement across the work surface.

  • UV Sterilization: Optional UV light for surface decontamination.

  • Alarm Systems: Alerts for airflow disruption or filter failure.

  • Ergonomic Design: Sloped front sash and adjustable height for user comfort.

  • Glove Ports (Class III): Gas-tight access for high-risk pathogen handling.

  • Energy-Efficient Fans: Reduce power consumption while maintaining performance.

  • Easy Maintenance: Removable filters and smooth surfaces for cleaning.

⚙️ Functionality

Biological Safety Cabinets operate by drawing air into the cabinet through front openings, filtering it via HEPA systems, and directing it in a controlled manner to protect:

  • Personnel: Prevents exposure to aerosols and pathogens.

  • Product: Maintains sterile conditions for sensitive samples.

  • Environment: Ensures contaminants are not released into the lab.

Airflow patterns vary by class, with some cabinets recirculating filtered air and others exhausting it completely to external systems.

🧬 Types of Biological Safety Cabinets

There are three main classes, each suited for different biosafety levels and applications:

ClassProtection LevelAirflow TypeUse Case
Class IPersonnel & EnvironmentInward airflow, exhaust through HEPALow to moderate risk work (BSL-1, BSL-2)
Class II (A1, A2, B1, B2)Personnel, Product & EnvironmentLaminar airflow, partial or full exhaustCell culture, viral studies, sterile product prep
Class IIIMaximum containmentSealed glove ports, full exhaustBSL-4 pathogens, toxic chemical


🧪 Use Cases

Biological Safety Cabinets are indispensable in:

  • Microbiology & Virology Labs: Safe handling of infectious agents.

  • Pharmaceutical Manufacturing: Sterile compounding and drug development.

  • Clinical Diagnostics: Sample preparation and pathogen testing.

  • Biotech & Genetic Engineering: Cell culture and recombinant DNA work.

  • Public Health & Epidemiology: Containment of emerging diseases.

  • Academic Research: Teaching and experimentation in biosafety protocols.


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